The WHO recommends the use of the RTS,S/AS01 (RTS,S) malaria vaccine among children in subSaharan Africa and in other regions with moderate to high P. falciparum malaria transmission.
The WHO’s recommendation was based on the results from an ongoing pilot programme in Ghana, Kenya and Malawi.
Malaria remains a primary cause of childhood illness and death in subSaharan Africa, according to the WHO.
Malaria Disease
Malaria is a mosquito-borne disease caused by a plasmodium parasite that commonly infects a certain type of mosquito (female Anopheles mosquitoes) which feeds on humans.
Children aged under 5 years are the most vulnerable group affected by malaria.
There are 5 parasite species that cause malaria in humans, and 2 of these species – P. falciparum and P. vivax – pose the greatest threat.
In 2018, P. falciparum accounted for 99.7% of estimated malaria cases in the WHO African Region 50% of cases in the WHO South-East Asia Region, 71% of cases in the Eastern Mediterranean and 65% in the Western Pacific.
P. vivax is the predominant parasite in the WHO Region of the Americas, representing 75% of malaria cases.