A mysterious man, Griffin, referred to as 'the stranger', arrives at the local inn owned by Mr. and Mrs. Hall of the English village of Iping, West Sussex, during a snowstorm. The stranger wears a long-sleeved, thick coat and gloves; his face is hidden entirely by bandages except for a prosthetic nose, and he wears a wide-brimmed hat. He is excessively reclusive, irascible, unfriendly, and introverted. He demands to be left alone and spends most of his time in his rooms working with a set of chemicals and laboratory apparatus, only venturing out at night. He also causes a lot of accidents, but when Mrs. Hall addresses this, the stranger angrily demands to put it on his bill. While Griffin is staying at the inn, hundreds of strange glass bottles arrive. Many local townspeople believe this to be very odd. He becomes the talk of the village with many theorizing as to his origins.
Meanwhile, a mysterious burglary occurs in the village. Griffin is running out of money and is trying to find a way to pay for his board and lodging. When his landlady demands that he pay his bill and quit the premises, he reveals his invisibility to her in a fit of anger. An attempt to apprehend the stranger by police officer Jaffers is thwarted when he undresses to take advantage of his invisibility, fights off his would-be captors, and flees to the downs.
